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But reduced production tells only half the story

If it was hydroxocobalamin then you're extremely unlikely to get an allergic reaction to it on subsequent jabs

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"Vitamin E protected the mouse adrenal gland against immobilization stress." Polish Journal of Veterinary Sciences (2022): 447-454

The AACE/ACE suggests intensifying treatment for people with diabetes whose postprandial glucose levels are not at the target level of less than 140 mg/dL