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Epub 2008 Nov 18

Peer review Peer review information Nature Reviews Rheumatology thanks Tak-Mao Chan, Mariele Gatto and the other, anonymous, reviewers for their contribution to the peer review of this work

Standard practice is to dose bupropion in the morning

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Discovered in 2015 by Changhan David Lee and Pinchas Cohen at USC, MOTS-c is encoded in the 12S rRNA region of the mitochondrial genomemaking it one of a small but growing family of mitochondrial-derived peptides (MDPs) that challenge the longstanding view of mitochondria as passive energy factories