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doi: 10.2147/JPR.S306280 [DOI] [PMC free article] [PubMed] [Google Scholar] 2

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To induce this transformation, tumor cells secrete signaling molecules (e.g., Wnt7a [60], and osteopontin [61, 62]), and release exosomes containing miRNAs (e.g., miR-9 [63] or miR-125b [64]) and proteins like survivin [65]

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