However, it is essential to continue monitoring as prescribed, particularly during dose escalation, to ensure glucose levels remain within target ranges
As with other GLP-1-based therapies, the most frequently reported side effects of retatrutide particularly during the initiation and dose-escalation phases are gastrointestinal in nature
Meanwhile, Ozempic and related medications like Wegovy continue providing proven benefits for millions of patients
Featured photo at top of a semaglutide injection pen
Last reviewed: May 21, 2026 Last updated: May 21, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations