This discovery gives us a basic understanding of how having kidney disease impacts cardiometabolic health by increasing resistance to the effects of these important hormones, explained Baback Roshanravan, professor of nephrology and a senior investigator on this project
Surprisingly, given the limited amount of training data, we found that an ensemble of multi-task convolutional neural-network (CNN) models that simultaneously predict potency at both GCGR and GLP-1R provides significantly better performance against GLP-1R, whereas performance differences against GCGR were largely not significant
You might have heard about a type of medication called GLP-1s, which stands for glucagon-like-peptide-1 agonists
Sen and study co-authors, associate professor Dr Nadia Hernandez, and assistant professor Dr Christina Goehl, who are subspecialised anaesthesiologists with expertise in point-of-care ultrasound that allows bedside assessment of stomach contents
Leaving the vial on a counter or in a warm room for extended periods accelerates peptide degradation
