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Local control after stereotactic radiosurgery for brain metastases in patients with melanoma with and without BRAF mutation and treatment

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Serum metabolomic studies, including some described in the prior sections, identified lipid metabolite clusters associated with TBI at 24 h [30, 31, 47] and 4 days [30] after injury using sera from TBI and control patients ( Table 2)

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In connection with its high lipophilicity causing solubility problems ibuprofen poorly penetrates across the BBB