It has found that inhibition of the PI3K/AKT/mTOR signaling pathway blocks the process of aerobic glycolysis (e.g., decreased lactate production) in cells, and these studies speculate that it may regulate the expression of the PFKFB3 of aerobic glycolysis (135)
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Apelin is a positive regulator of ACE2 in failing hearts
528 Excess irons can promote the progression of atherosclerosis by affecting macrophages, and a balanced intracellular iron environment is crucial in alleviating atherosclerosis