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Given the association of GSSG with the oxidative protein folding environment in the ER, we examined whether etomoxir could make the ER more oxidizing to proteins in the lumen

This effect may be attributed to its modulation of molecular pathways involving matrix metalloproteinase (MMP)-2 and MMP-9 expression, as well as nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 2 gene (NOX2) levels

Cellular nanosponges Inhibit SARS-CoV-2 Infectivity

Cyclophosphamide-induced apoptosis in COV434 human granulosa cells involves oxidative stress and glutathione depletion

As a result, glutathione remains ineffective as it is not enough to fight off oxidative stress