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[DOI] [PubMed] [Google Scholar] 50.Meister A., Anderson M.E

383 SIRT5-catalyzed demalonylation and inactivation of SDHA block the TCA cycle and induce succinate accumulation, promoting tumorigenesis and drug resistance

22 Hyperglycemia-driven ROS overproduction predominantly arises from two mechanisms: 66 Glucose Autoxidation (animal model, in vitro data): Direct generation of ROS via glucose metabolism intermediates by NOS, NADPH oxidases, xanthine oxidase, and hemeperoxidase enzymes, such as myeloperoxidase

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There is also emerging evidence suggesting its benefits in preventing severe cases of COVID-19 and long COVID