The biggest difficulty most people will encounter today with GLP-1 drugs is going to be the cost
doi: 10.3389/fphar.2025.1591825 Received 11 March 2025 Accepted 28 August 2025 Published 08 October 2025 Volume 16 - 2025 Edited by Er Sheng Gong, Gannan Medical University, China Reviewed by Guillermo Federico Spitzmaul, National Scientific and Technical Research Council (CONICET), Argentina Leonardo Dionisio, National Scientific and Technical Research Council (CONICET), Argentina Updates Copyright 2025 Giannini, Soldi, Elli, Sagheddu, Castagnetti, Viciani, Salvini, Battistuzzi, Milazzo, Alibrandi and Sidoti
68 Proinsulin synthesis is induced in islet beta-cells when plasma glucose levels are greater than 2mM, ensuring that there is a sufficient reservoir of insulin secretory stores available for when secretion is needed to promote nutrient uptake from the circulation into tissues
This study also aimed at exploring potential differences in the effects of cannabis on endocrine outcomes when administered via different routes
LETTERS TO THE EDITOR Proctocolitis Caused by Coffee Enemas Bora Keum Yoon Tae Jeen Sung Chul Park Yeon Seok Seo Yong Sik Kim Hoon Jai Chun Soon Ho Um Chang Duck Kim Ho Sang Ryu American Journal of Gastroenterology 105(1):p 229-230, January 2010