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In two Phase 3 studies, a fixed-dose combination of cagrilintide and semaglutide (each at 2.4 mg) was associated with weight reductions of 20.4% and 10.4% (placebo subtracted) after once-weekly subcutaneous injection for 68 weeks in overweight/obese individuals without and with type 2 diabetes, respectively (Table 2) [68]

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