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Among the intestinal L cell peptides, glucagon-like peptide-1 (GLP-1) has been highlighted because of the success of its recent clinical use in the treatment of diabetes mellitus and obesity [2]
Perkovic V, Jardine MJ, Neal B, Bompoint S, Heerspink HJL, Charytan DM, et al
10.1038/nrneph.2017.123 [DOI] [PubMed] [Google Scholar] 85
RESULTS Pathophysiology GLP-1 receptor agonists cause a significant decrease in alcohol use by inhibiting and modulating dopaminergic neurons present in the central areas of the mesolimbic reward system, namely, the ventral tegmental area (VTA) and the nucleus accumbens (NAc)
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