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note: Do not exceed recommended daily dose (10 g)

GLS1, encoded by the GLS gene on human chromosome 2, is inactive in the dimer state and activated in the phosphorylation state which it assembled into tetramers

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Open 8 (6), e2514857

A report from the EMAs PRAC, published on 12 April 2024, said: After reviewing the available evidence from non-clinical studies, clinical trials, post-marketing surveillance data and the available studies the PRAC considers that no update to the product information is warranted. The PRAC statement said that market authorisation holders would continue to monitor events, including new studies, as part of their pharmacovigilance activities