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8,9 Besides direct activation, the gut microbiota also indirectly regulates innate immunity through its metabolic products
Cells were fixed with 4% paraformaldehyde for 30 min and washed with non-permeabilizing or permeabilizing PBS containing 0.025% Triton-X
Mitochondria, the centres of cellular energy metabolism, exhibit unique biological characteristics during oocyte development.Compared with the typical branching morphology and structure of somatic mitochondria containing abundant crista, mitochondria in human oocytes and early embryos (up to the mulberry embryo stage) present a special round/cap-like morphology and poorly developed cristae, which leads to a significant reduction in their oxidative phosphorylation efficiency
It also appears to support the activity of dermal fibroblasts, the cells responsible for producing these structural proteins
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