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Pharm Res (2022) 39(6):123348

Results: The total number of CRC cases in the whole population was 1014970 and a total of 3105 cases of CRC were found in 151105 cases of PLA

Future GLP-2 trials in IBD should stratify patients by disease phenotype (mucosal UC, inflammatory CD, stricturing CD) and incorporate serial cross-sectional imaging to monitor for stricture progression, given the mechanistic link between GLP-2R signaling through subepithelial myofibroblasts and intestinal fibrogenesis

Medication shortages have affected both semaglutide and tirzepatide products at various times