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For example, selenium-containing nanomicelles (PEGPUSePEG/Pt) respond to elevated intracellular GSH by reducing platinum ions from the micelle core, thereby releasing encapsulated doxorubicin (DOX)

Summary of the AOP Events: Molecular Initiating Events (MIE) Key Events (KE) Adverse Outcomes (AO) Relationships Between Two Key Events (Including MIEs and AOs) Network View Prototypical Stressors Life Stage Applicability Taxonomic Applicability Sex Applicability Overall Assessment of the AOP Biological plausibility, empirical support and quantitative understanding of the KERs and the evidence that uphold essentialities of KEs in this AOP were analyzed together for the overall assessment of an AOP

Enhanced Efficacy - By encapsulating active ingredients in liposomes, their stability and bioavailability are significantly improved