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Typically, gastrointestinal (GI) side effects of GLP-1s, such as nausea and vomiting, are dose-dependent, mild-to-moderate in severity and occur mostly during initiation of therapy and up-titration

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Folic Acid: Folic Acid (Vitamin B9) is essential for DNA synthesis, cell division, and overall growth

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Accelerating dose escalation increases nausea, vomiting, and dropout rates without improving weight loss outcomes compared to the gradual 16-week protocol supported by clinical evidence