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Its also in Phase 3 trials and not yet FDA approved

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Second, NNMT depletes that universal methyl donor, SAM, which is essential for DNA methylation, neurotransmitter production, and other indispensable biological processes

Culturing was performed in RPMI 1640 medium enriched with 10% fetal bovine serum, maintained at 37C in a humidified incubator with an atmosphere of 5% CO 2 and 95% air