However, it has poor water solubility and bioavailability, which can limit its effectiveness [16]
What the animal studies cannot tell us includes optimal human dosing, population-specific responses (elderly, children, pregnancy), long-term safety in humans, rare side effects that require large sample sizes to detect, and interactions with medications or medical conditions
Moreover, other genetic traits, such as the functional deficiencies in cobalamin-dependent methionine synthase described above, could contribute to an increased relative risk of cardiovascular disease, but their respective contributions are not yet determined
In contrast, the 5-pack is better value for longer protocols, multiple concurrent studies, or bulk research use
Stomach Pain: Consider having this medicine after a meal to reduce stomach discomfort