Causes In most cases, pathologically elevated cobalamin levels underlie certain diseases or organ dysfunctions , especially those affecting liver tissue
Mental illnesses including depression and seasonal affective disorder often correlate with suboptimal B12 levels , particularly during winter months when natural Vitamin D3 synthesis decreases
Symptoms of low levels of Vitamin B12 in your body include anemia, weakness, fatigue, heart palpitations, pale skin, constipation, diarrhea, bloating, loos of appetite, nerve problems such as tingling or numbness, muscle weakness, loss of vision, mental problems such as changes in mood and depression
Phase 2 trials ran 12 weeks (METAOD005) and 24 weeks (METAOD006/OPTIONS)
Discard any remaining solution after that, even if the vial still has liquid in it