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GIP, or glucose-dependent insulinotropic polypeptide, is another gut hormone that: Stimulates insulin release Supports fat metabolism May contribute to enhanced weight loss when paired with GLP-1 By acting on both pathways, tirzepatide delivers a synergistic effect that may produce greater results than GLP-1 alone

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136,137,138 Research and clinical trials have shown that tirzepatide not only improves blood sugar levels but also has a positive impact on cardiovascular risk factors

Direct Liver Impact: It has a profound effect on reducing liver fat (hepatic steatosis)

For most people, it can take a few months to notice a change in weight