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Mitochondrial stress accelerates and amplifies these pathological processes, creating a self-reinforcing cycle of oxidative injury, impaired bioenergetics, and cardiometabolic dysfunction (1-2)

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However, this study found no changes in serum T3 and T4 levels [38]

doi:10.1111/vec.13234

Second, and most importantly for experimental design, MT-2 is a non-selective melanocortin agonist