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[DOI] [PMC free article] [PubMed] [Google Scholar] 197.Sudbery P, Gow N, Berman J

Geldanamycin and its 17-allyl-amino-a7-demethoxy analogue overcome Ad-mda7 resistance in lung cancer

While the passive technique focuses on drug and vehicle interaction and optimization to affect the stratum corneum structure, the active approach utilizes external energy to facilitate the transportation of drugs through the skin or by physically disrupting the outermost layer of the skin, known as the stratum corneum [230, 231]