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Given that vagal afferents innervate the ENS, it is plausible that the ENS can relay local intestinal signaling mechanisms to the CNS

doi:10.1055/s-0034-1390481

Where there is reduced access to GLP-1 RAs, support people with type 2 diabetes to access to structured education and weight management programmes where available

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Safety and Interaction Considerations Consumers evaluating supplements affecting metabolic pathways should consider potential interaction risks reported in scientific literature