Athauda D, Maclagan K, Skene SS, Bajwa-Joseph M, Letchford D, Chowdhury K, Hibbert S, Budnik N, Zampedri L, Dickson J, Li Y, Aviles-Olmos I, Warner TT, Limousin P, Lees AJ, Greig NH, Tebbs S, Foltynie T (2017) Exenatide once weekly versus placebo in Parkinsons disease: a randomised, double-blind, placebo-controlled trial
GLP-1 medications require a washout period before pregnancy but do not carry the same level of birth defect risk
But the downstream part is very clear
And the gut microbiome produces neurotransmitters, short-chain fatty acids, and inflammatory mediators that directly influence brain function
Surgeries involving the stomach or the esophagus, such as bariatric surgery or procedures for acid reflux, can sometimes damage the vagal nerves, which can lead to the onset of gastroparesis