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This heightened expression has been observed to result in a substantial reduction in patient survival, a phenomenon that is attributed to the enzymes capacity to enhance glutamine metabolism within cancerous cells

doi:10.1021/ja0115013

Prez R, Castilla-Cortzar I, Nez M, Prado A, Mirpuri E, Garca M, Gonzlez Barn S, Picardi A: IGF-I does not improve fat malabsorption in cirrhotic rats

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