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Further investigation revealed that treating control organoids with 5 M A led to a significant downregulation of TMSB4X expression, thereby establishing a functional link between A pathology and reduced T4 levels

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Abbreviations L-ca: L-carnitine MSG: Monosodium Glutamate MDA: Malondialdehyde Ca: Calcium P: Phosphorous PCT: Proximal convoluted tubule DCT: Distal convoluted tubule ROS: Reactive oxygen species SOD: Superoxide dismutase BUN: Blood urea nitrogen GPX: Glutathione peroxidase ELISA: Enzyme linked immunosorbent assay APAF1: Apoptotic protease activating factor 1 CAT: Catalase References Quines CB, Rosa SG, Da Rocha JT, Gai BM, Bortolatto CF, Duarte MMM, Nogueira CW

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