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Mozaffarian D et al

The effect of subcutaneous dulaglutide on weight loss in patients with Type 2 diabetes mellitus: Systematic review and meta-analysis of randomized controlled trials

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People Taking Orforglipron Saw Substantial Reductions in Weight and A1C Levels In a 40-week placebo-controlled trial, people with type 2 diabetes taking the highest dose of orforglipron lost 16 pounds on average, or about 7.9 percent of their body weight, and were still losing weight when the study ended

Bruemmer says its an essential component of any ultimately successful treatment