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The exquisite immune specificity for beta cells suggests that such cells may already harbour molecular signatures of vulnerability, which may act not only as initiators or conduits for the early immune response but also as amplifiers of ongoing beta cell-directed immune destruction (Kracht et al

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It has been demonstrated that the production of PGC-1 protein is inversely proportional to the concentration of A (Qin et al., 2009

Sleep 31(4):47380 Thase ME, Murck H, Post A (2010) Clinical relevance of disturbances of sleep and vigilance in major depressive disorder: a review