However, for women with compromised glutathione status (PCOS, IVF conception, gestational blood sugar issues, poor diet, environmental exposures), even therapeutic doses may generate toxic metabolites that affect fetal brain development
Self-reported weight and height were used to estimate body mass index (BMI) prior to the initiation of semaglutide
For acute gastrointestinal losses, medically formulated oral rehydration salts (ORS) available from pharmacies are more appropriate than sports drinks
These medications are given at different doses
Practical dietary measures include: Eating smaller, more frequent meals rather than large portions Avoiding high-fat, fried, or heavily processed foods, which can worsen gut transit Reducing intake of alcohol, caffeine, and artificial sweeteners (particularly sorbitol and mannitol), all of which can exacerbate loose stools Temporarily reducing insoluble fibre (found in wholegrain cereals, raw vegetables, and bran) if these appear to worsen symptoms Staying well hydrated oral rehydration salts (ORS), available from pharmacies, are recommended to replace fluid and electrolytes lost during diarrhoea
