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Results: After high glucose treatment, the proliferation viability of HK2 cells decreased, the apoptosis rate and ROS production increased (P 28, 30.23 kg/m 2

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Abbreviations AGER: Advanced Glycation End-product Receptor Akt: Protein kinase B COX-2: Cyclooxygenase-2 GnRH: Gonadotropin-releasing Hormone GPX4: Glutathione peroxidase 4 GSH: Glutathione IFN-: Interferon-gamma IL-1: Interleukin-1 IL-6: Interleukin-6 IL-8: Interleukin-8 JAK: Janus Kinase KIR: Killer cell inhibitory receptor MALAT1: Metastasis-associated lung adenocarcinoma transcript 1 MAPK/Erk1/2: Mitogen-activated protein kinase / Extracellular signalregulated kinase 1/2 MCP-1: Monocyte chemoattractant protein-1 MIF: Macrophage migration inhibitory factor MMP: Matrix metalloproteinase NF-B: Nuclear Factor Kappa-light-chain-enhancer of Activated B cells NRF2: Nuclear factor erythroid 2related factor 2 (NFE2L2) SCFAs: Short-chain fatty acids SLC7A11: Solute carrier family 7 member 11 STAT: Signal Transducer and Activator of Transcription TFRC: Transferrin receptor (protein 1) TGF-: Transforming growth factor TNF-: Tumor Necrosis Factor Alpha VEGF: Vascular endothelial growth factor References WHO, Endometriosis (2023) [Available from: Saunders PTK, Horne AW (2021) Endometriosis: etiology, pathobiology, and therapeutic prospects

Some individuals have reported serious digestive and intestinal side effects while taking Accutane