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Clinical complications related to liver failure and portal hypertension, such as hepatic encephalopathy, symptomatic ascites, repeated hospitalizations, medication burden, electrolyte imbalances (especially hyponatremia), low sodium diets, and general debility, exacerbate appetite loss (13)

A 2003 meta-analysis of 21 trials found that ALCAR was superior to placebo in several psychometric tests assessing global patient functioning, attention, memory, and some intellectual functions (105)

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J., Deng, J