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10.1186/s12868-016-0274-7 128 RudanIWrightA

Dynamics of peptide-TMD interactions are correlated with the allosteric effect of G proteins on agonist affinity and G protein conformation The stark contrast in the requirement for stable TMD interactions for exendin-P5 affinity relative to GLP-1, oxyntomodulin and exendin-4, raises important questions regarding molecular mechanisms for peptide binding and receptor activation

Environmental Triggers: Factors like stress, skin injury (Koebner phenomenon), sunburn, or exposure to certain chemicals may initiate or worsen vitiligo

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Biologically, removing dysfunctional cells allows the body to relocate resources to younger, healthier cells