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Pushing a patient past their tolerability threshold often leads to protocol abandonment

[13] preliminarily established reference intervals for serum GR activity in apparently healthy adults in Zhongshan, China, reporting ranges of 3672 U/l for males, 3865 U/l for females aged 1850 years, and 4567 U/l for females aged 51 years and older

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CXCR4 signaling activates NF-B, which upregulates the transcription of NLRP3 and pro-IL-1, preparing the stage for inflammasome assembly (Fig