Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, Parks EJ
As of April 2025, the FDA received over 1,000 adverse event reports related to compounded semaglutide and tirzepatide
Why these four products together
Some medications to watch out for include: Medications used to treat type 1 or type 2 diabetes, including insulin or sulfonylureas (such as Amaryl or Glucotrol XL) Wegovy causes a delay in gastric emptying, so it has the potential to impact the absorption of medications that are taken by mouth at the same time
With new data expected this month from the Lillys SURMOUNT-2 trial, analysts are predicting up to $52B in peak sales of tirzepatide (for T2D, obesity, and other indications)