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Pharmacological interventions such as orlistat or GLP-1 receptor agonists may be considered for patients with BMI 30 kg/m who have not achieved adequate weight loss through lifestyle measures alone

Uncertain Effectiveness : Promising animal data do not prove reliable human benefit, and limited clinical evidence prevents firm conclusions about recovery, pain, or tissue repair outcomes

When administered together, these compounds can help improve fat burning, reduce fatigue, and support overall metabolic health

Third, the scope of this review is limited to studies published up to the present date

Systemic reactions: Rapid heart rate, shortness of breath, or signs of anaphylaxis (hives, swelling, difficulty breathing) in rare cases