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Initial crystal conditions were identified using the commercially available JBScreen LCP crystallization screen and further optimized using grid screening to the final crystallization condition of 0.1 M (NH 4 ) 2 PO 4 , 0.1 M Hepes 7.0, 32% PEG 400, 6 mM TCEP
Elevated TMAO levels hurt cardiomyocyte mechanics and intracellular calcium handling, and the cardiomyocytes exhibited glycogen accumulation, a higher number of mitochondria, and lipofuscin-like pigment deposition after TMAO exposure
This is particularly important for B-vitamin preparations, which can cause anaphylactic reactions in sensitized individuals
Cancer Res 63(12):34033412 Carson-Walter EB et al (2001) Cell surface tumor endothelial markers are conserved in mice and humans
Smad proteins and transforming growth factor-beta signaling
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