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The g/kg band does not change by molecule, but the rate of loss often does tirzepatide on the Tirzepatide Injection protocol typically drives faster early loss than semaglutide on the Semaglutide Injection protocol

The primary drivers behind this effect are a group of antioxidants known as polyphenols, specifically a catechin called epigallocatechin gallate (EGCG)

We see increasing numbers of more severe and treatment-refractory cases with iatrogenic factors, multiple comorbidities and advanced age, and increasingly often, patients require hospital admission and inpatient treatment for gout flare

For these individuals, strict avoidance remains the only medically sound treatment

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