glp 1 vs weight loss surgery GLP-1 vs. Bariatric Surgery: 1- Surgery: 25-30% + TBWL for 10+ years GLP-1: 15-21% in trials, less in real-world 2- Metabolic Benefits: > GLP-1 3- Comorbidities: Greater resolution with 5 Reasons Bariatric Surgery Might

A fascinating recent paper by Dr David Juurlink from the University of Toronto and the Ontario Poison Centre gives an excellent summary of the (admittedly limited) evidence we have to date supporting this novel therapy

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Always start under physician supervision with gradual dose escalation

Biologics, despite their effectiveness, are often reserved as a last resort due to limitations like cost and potential side effects (54, 55)

We recently reported studies examining a novel glycolipid surfactant-peptide conjugation technology designed to prolong in vivo terminal elimination half-life (T 1/2 ) and demonstrated its tunable impact on pharmacokinetic (PK) parameters for analogs of both parathyroid hormone 19 and GLP-1R/GCGR dual agonists 20