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Therefore, glycocalyx damage not only manifests as local pathologic changes in the organ but is also likely to be one of the common pathologic mechanisms for the progression of SAP to MODS

Weeks 1-4: Foundation phase The first month establishes tolerance and begins the cellular changes that eventually produce visible results

57 When telomerase is inactive in cells, antigen-presenting cells transfer telomeres to recipient T cells through extracellular vesicles (EVs), which can extend the telomere length of T cells more than 30-fold, thereby protecting recipient T cells from replicative aging and prolonging the lifespan of the immune system