[7] [8] Mosjov y sus colaboradores Daniel J
In addition to its direct effects on beta cells, GIP also leads to increased glucagon secretion, and indirectly results in increased insulin secretion via communication between the alpha and beta cells of the pancreas ( via complex mechanisms, including stimulation of somatostatin secretion, which inhibits glucagon secretion, and indirectly via stimulation of insulin production, which then inhibits glucagon release ( Figure 1 Incretin action plays a large role on post-prandial secretion of insulin, and may account for up to 70% of hormone release ( Both incretins have effects outside the pancreas
They work best when combined with practical, sustainable health habits: Consistent meals with adequate protein, fiber, heathy fats and fluid Eating well consistently with meal planning and gentle prep ahead Strength training and aerobic activity each week
Holst JJ, Nauck MA, Deacon CF, rskov C
Long-Term Safety: Although GLP-1 medications have demonstrated efficacy and safety in clinical trials, their long-term safety profile is still being evaluated