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10.1016/j.theriogenology.2017.03.029 64 NazariL.SalehpourS.HosseiniS.SaharkhizN.AziziE.HashemiT.et al (2020)

doi: 10.1126/sciadv.1500183 28 CoyleC.CaffertyF

PMCID: PMC4665094

Vitamin C may support stress and immune resilience for frequent caffeine users

It is also possible that in active acromegaly, chronic exposure to elevated IGF-I levels resets IGF-IR responsiveness via the induction of IGF-IR resistance (70), as it has been demonstrated that prolonged stimulation with IGF-I induces functional IGF-IR resistance in vitro through the negative feedback loop (72)