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BJU International, 87 (1), 7581

2025;24(1):e14340

The ROS produced are converted to peroxynitrite, which has a very strong cytotoxic effect when combined with NO, resulting in direct damage to vascular wall cells and a decrease in the biological activity of NO in vascular endothelial cells and vascular smooth muscle cells [68]

Hydration: Drinking enough water and including water-rich foods (such as soups, cucumbers, and melons) can help prevent dehydration, which is important because GLP-1 medications may increase fluid loss

These results imply that the function of the MPC contributes to metabolic dysfunction and that targeted pharmacological interference with the MPC in humans may exert beneficial health effects