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The pivotal role that IGF-1 plays in cell growth and proliferation, combined with the apparent protection against post-natal development of malignancies conferred by congenital IGF-1 deficiency, suggests a possible involvement of IGF-1 in the development of cancer [48]

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[DOI] [PubMed] [Google Scholar] 89.Simakou T, Butcher JP, Reid S, Henriquez FL

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