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Glutamine is the most abundant amino acid and a crucial energy substrate, as well as an important nitrogen and carbon donor for various biosynthetic precursors

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MBOAT1 was also identified in a recent genetic screen for ferroptosis suppressors, and was shown to be positively regulated by ER signalling in ER+ breast cancer cells 52

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460 In recent years, several molecular pathways with simultaneously large/microvascular protective effects have been identified (PPAR-, CXCR4, etc.), but most of them are still in animal experiments or phase I clinical stage