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What makes them unique among other T2D drugs is their concurrent ability to reduce food intake, a great benefit considering the frequent comorbidity of T2D and obesity

Further, SAR experiments focused on residue-by-residue optimization of 1907 to identify residues that were critical to activity

During this 1620 week optimization window, your body adjusts to the medication, appetite suppression stabilizes, and weight loss momentum builds

It will require embedding kidney testing into diabetes and hypertension workflows, and aligning reimbursement to reward prevention, not just downstream dialysis care

So there is a little bit of concern about that. Its a concern that has been pervasive enough for existing drugs that Lilly released a commercial ahead of the 2024 Oscars urging against vanity use