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Consejos para resultados ptimos: Comienza con 1,5 g para evaluar la tolerancia

Immunohistochemistry Immunohistochemistry was performed as previously detailed [5] using the following primary antibodies: rabbit anti-CHGA (1:400, SP-1, ImmunoStar, Hudson, WI, USA), guinea pig anti-glucagon (1:2500, M8707, Euro-Diagnostica, Malm, Sweden), goat anti-GIP (1:500, sc-23554, Santa Cruz Biotechnology, Dallas, TX, USA), rabbit anti-INSIG1 (1:100, ab70784, Abcam, Cambridge, UK) rabbit anti-SCD1 (1:250, #2794, Cell Signalling Technology, Danvers, MA, USA), rabbit anti-SQLE (1:100, Life Technologies, Waltham, MA, USA) and rabbit anti-SREBP2 (1:1000, ab28482, Abcam, Cambridge, UK)

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Although GLP-1RAs exhibit certain potential in some metabolic and inflammatory diseases, their use as a treatment option for sepsis-induced muscle atrophy still faces numerous limitations, particularly concerning insufficient clinical evidence, complex therapeutic mechanisms, drug side effects and individual variability