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Some of the most powerful evidence supporting the critical role that glutamate plays in the pathology of ALS is the effectiveness of the medication riluzole, which inhibits glutamates effects on the nervous system

The samples were centrifuged at 1000 rpm for 3 min using a KUBOTA 3520 (KUBOTA, Tokyo, Japan), and absorbance was measured at 595 nm using a GeneQuant 1300 spectrophotometer (Biochrome, Cambridge, UK)

Advances in gerontology = Uspekhi gerontologii , 20 (1), 7485

Statements Author contributions SM, SP, MA, DeL, PK, SA, FN and JR conceived of the article, compiled the literature, and interpreted its contents

doi: 10.1210/clinem/dgaa644 5