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Identification of polymorphisms in the 5-regulatory and exon 1 regions, and association with human liver UGT1A6 gene expression and glucuronidation

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Although not all omega-3 PUFAs trials have shown beneficial in reducing the symptomatology of migraine, further research is needed to fully establish their clinical efficacy and understand the precise molecular mechanisms underlying the effects of omega-3 PUFAs and PUFA-derived lipid mediators, SPMs on migraine pathophysiology and progression

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