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(2012) demonstrated: Statistically significant reductions in visceral adipose tissue of approximately 1518% over 26 weeks compared to placebo Meaningful increases in IGF-1 levels Improvements in triglyceride profiles in some patient subgroups Effects were partially reversed upon discontinuation, suggesting that sustained benefit requires ongoing therapy The consistency of the VAT reduction finding across multiple trials is what anchors tesamorelin's clinical utility

Acknowledgements We thank David Fay, PhD (Miller Scientific) for assistance with the literature review and data extraction

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This attachment might make the receptor change its shape, which could start cell signals, mainly those involving G-proteins